Sézary cell.

Sézary cells (SC) (synonyms: mycosis cell, Lutzner cell, cerebriform lymphocytes, Atypia Cellules Monstreuses or monster cell) are atypical lymphocytes with a grooved or cerebriform nucleus seen both in tissue and blood. They are characteristically seen in cutaneous T cell lymphomas including mycosis fungoides (MF). The Sézary cell is named after the French dermatologist Sézary A (1880-1956). Sézary and Bouvrain described the leukemic variant of MF in 1938 where they identified the monster cells with atypical features. This variant is now known as Sézary syndrome. In 1968, Lutzner and Jordan described the ultrastructural details of Sézary cells.